Tadalafil generic is a substance capable of inhibiting the fifth type of phosphodiesterase hormone, which relaxes the smooth muscle cells and actively fills the cavernous bodies of the male penis. Increased blood flow to the perineum occurs due to the vasodilating effect of tadalafil, when the cavernous arteries become wider and contain much more blood. This effect improves the response to natural stimulation, which means a significant increase in potency. Tadalafil generic is a regulator of potency, so it is contained in drugs designed to treat erectile dysfunction in men.
Tadalafil Generic properties and the principle of action
Generic Tadalafil 20mg increases the hardness of the penis by relaxing the tone of the smooth muscles of the arteries and increasing the flow of blood to the genitals. The amount of blood filling the penis is regulated by the production of nitric oxide. Also, the main component of Cialis stimulates the release of nitric oxide and inhibits the production of phosphodiesterase of the fifth type, which is tadalista 20 responsible for the reverse process – the compression of the vessels of the penis and the cessation of erection.
The drug has a fairly pronounced hypotensive effect, so people with cardiovascular diseases should consult with the doctor in charge. In no case can it be combined with drugs from hypertension, as well as with alcohol. But, in comparison with Viagra, he is more patient with alcoholic beverages and tasty food, which made him such a popular stimulator for the weekend.
Tadalafil Generic: when to take?
Tablets with tadalafil generic intended for the treatment of erectile disorders in men of different ages. They are shown in such cases:
- with insufficient erection;
- when there are difficulties with achieving orgasm;
- if often worried about premature ejaculation;
- when there is no desire to have sex;
- with a reduction in the number or total absence of erections.
Taladafil is used for the symptomatic treatment of impotence in men from 18 years of age, as well as in the complex therapy of erectile disorders. It is effective for treating male impotence caused by various factors (diseases of the genitourinary system, diabetes, spinal cord injuries, psychoemotional disorders, after removal of the prostate gland). Tablets are drunk about half an hour before intimacy, washed down with plain water. The standard dose is 20 mg per day. Dosage can be adjusted on an individual basis at the discretion of the doctor.
Tadalafil Generic: features of use
Drugs with tadalafil generic refer to medicines, so they tend to have some contraindications to use. Such tablets do not accept:
- people with an individual intolerance to the active substance;
- suffering from complicated diseases of the liver and kidneys;
- patients with heart problems who have recently had a heart attack or stroke;
- women and children.
With caution appoint hypo-and hypertensive patients, patients with leukemia, myeloma, diseases of the retina of the eye or with deformation of the penis. This substance is not compatible with some medications, so before using it, consult a physician.
The results of Generic Tadalafil’s research
The general population of patients with erectile dysfunction
Seven studies included more than 1500 men aged 21-87 years (mean age 59 years), among whom were people of different races and ethnicities. The patients had erectile dysfunction of varying degrees of complexity, etiology (organic, psychogenic, mixed) and a variety of concomitant diseases, including diabetes, arterial hypertension and other cardiovascular diseases. Most (more than 90%) patients experienced erectile dysfunction for more than 1 year.
In all 7 trials in the general population of patients with erectile dysfunction, a clinically significant and statistically significant improvement in erectile function in men who took tadalafil at doses of 5, 10 or 20 mg was observed, if compared with placebo; The effect of treatment did not decrease with time.
Efficacy in patients with diabetes mellitus
Patients with diabetes were included in all 7 basic studies of the general population of patients (N = 235) and 1 special study of the effectiveness of tadalafil in patients with type 1 and type 2 diabetes mellitus who had erectile dysfunction (N = 216). In this random, placebo-controlled, double-blind, parallel-group, prospective trial, tadalafil showed a clinically significant and statistically significant improvement in erectile function.
What side effects can Tadalafil Generic do?
Negative reactions of the body to the use of tadalafil generic often have an average and weak degree of severity. Most often, they appear after the first use of the drug and subsequently decrease as Cialis continues to use. The most common side effects are:
- headache – 11% of cases;
- dyspepsia – 7%.
Possible side effects include:
- the flush of blood to the face and its redness;
- congestion of the nasal cavity;
Rarely from admission tadalafil in humans appear:
- Pain in the eyes;
- edema of the eyelids;
Very rarely Tadalafil becomes the cause:
- blurry vision;
- rashes on the face;
- edema of the face;
- stomach ache;
- delayed erection.